Resistin

$379.00

Resistin (FIZZ3)

Brand

SKU: E50 Category:

Description

Intended use:

Resistin (FIZZ3) is a hormone influencing fat metabolism and inflammation processes. In humans, it is expressed in bone marrow and transported by macrophages into adipose tissue. Resistin stimulates pre-adipocyte proliferation and lipolysis of mature adipocytes probably by influencing MAPK signaling. With regard to the importance of Resistin in disorders of energy metabolism, a significant reduction could be shown in patients with anorexia nervosa. It has been demonstrated that Resistin enhances the expression of specific cell markers such as VACM-1 and ICAM-1 and thus may influence endothelial inflammatory processes, and thereby arteriosclerosis. Moreover, due to its association with Endothelin-1, Resistin also plays a role in cardiovascular diseases.

Resistin is relevant to medical conditions such as:
• Obesity
• Insulin resistance, diabetes
• Arteriosclerosis
• Inflammation
• Lipolysis

Specifications

Range: 20 – 1000 pg./ml
Sensitivity: 12 pg./ml
Incubation time: 4 hours
Sample volume: 15 µl (dilute 1:21; recommended)
Sample type:

Serum, plasma, cell culture medium, salvia, breast milk and urine.

Sample preparation:

Hemolytic samples appear to show falsely high Resistin levels. Whole blood should be chilled as soon as possible following collection. Serum and plasma samples are stable for maximal 2 days at room temperature. Long-term storage at -20°C, stable for maximal 2 years. Maximum 3 freeze/thaw cycles.

Reference values:

Women:   7.0 ng/ml +/- 2.5 SD (referred to BMI ~ 25 kg/m²)
Men:          6.0 ng/ml +/- 2.5 SD (referred to BMI ~ 25 kg/m²)

Species:

Human

Tests: 96 Tests
Method: ELISA
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