Periostin

$120.00

91 kDa homodimeric soluble extracellular matrix protein.

Brand

SKU: BI-20433 Category:

Description

Intended use:

Intended use:

Periostin (OSF-2) is secreted as a 91 kDa homodimeric soluble extracellular matrix protein expressed in collagen-rich fibrous connective tissues. Periostin is involved in osteoblast recruitment, attachment and spreading. It has been associated with the epithelial-mesenchymal transition in cancer and with the differentiation of mesenchyme in the developing heart. Periostin has functions in osteology, tissue repair, oncology, cardiovascular and respiratory diseases, and in various inflammatory settings. There are at least 7 isoforms of Periostin, caused by alternative splicing (http://www.uniprot.org/uniprot/Q15063).

Intended applications:

  • Osteology
  • Tissue repair
  • Respiratory diseases
  • Cardiovascular diseases
  • Oncology

Specifications

Range: 0 – 4000 pmol/l
Sensitivity: 62.5 pmol/l (STD2 125 pmol/l)
Incubation time: 5.5 hours
Sample volume: 10 μl
Sample type:

Serum, plasma

Sample preparation:

Centrifuge freshly collected blood as soon as possible. Store centrifuged samples at -20°C for longer storage. Samples are stable up to 4 freeze and thaw cycles. Hemolyzed or lipemic samples may cause erroneous results.

Reference values:

Median serum (n=24): 864 pmol/l
Med ian EDTA plasma (n=20): 817 pmol/l
Median heparin plasma (n=20): 891 pmol/l
Median citrate plasma (n=24): 885 pmol/l

Species:

Human

Tests: 96
Method: ELISA
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