| Intended use: |
Osteomark® NTX-Serumtest is used for the quantitative management of cross-linked N-telopeptides of type I collagen in human serum. The NTX molecule is bone specific due to the unique amino acid sequences of the cross-linked alpha-2 (I) N- telopeptide. Release of the NTX molecule is mediated by osteoclasts. Elevated levels of NTX indicate elevated bone resorption. NTX levels are used for: |
| Range: | 5 - 40 nM BCE | ||||||||||||||||
| Sensitivity: | 3.2 nM BCE | ||||||||||||||||
| Incubation time: | 2 hours | ||||||||||||||||
| Sample volume: | 50 µl (dilute 1:5) | ||||||||||||||||
| Sample type: |
Serum, cell culture |
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| Sample preparation: |
Specimen should be collected at the same time of the day. Store samples refrigerated at 2-8°C for up to 24 hours or frozen at -20 °C for longer storage. Stable up to 3 freeze and thaw cycles. |
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| Reference values: |
nmol Bone Collagen Equivalents per litre = nM BCE
Reference values from children are available. |
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| Species: |
Human, bovine, sheep, porcine, rabbit, rat, rhesus macaque |
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| Tests: | 96 Tests | ||||||||||||||||
| Method: | ELISA |