$120.00
Measurement of soluble human intermediate filament protein fragments of keratin 18 (K18)* that contain the M30 neo-epitope (K18Asp396-NE). Released from human epithelial cells.
| Brand |
|---|
| Intended use: |
The M30 neo-epitope (K18Asp396-NE) is a sensitive and integrative indicator specific for epithelial cell death involving caspase -3, -7 or -9 activation. Quantitative measurement of the apoptotic cell death biomarker K18Asp396-NE (“M30 antigen”) released from dying human epithelial cell lines in vitro or in vivo. The cells or tissues should be of human epithelial origin (e.g. kidney, gut, colon, lung or liver) expressing K18. * Note: |
| Range: | 40 – 1000 U/l (units are defined against a synthetic peptide standard containing the M30 and M5 epitopes; 1 U/l = 1.24 pM) |
| Sensitivity: | 20 U/l |
| Incubation time: | 4.5 hours |
| Sample volume: | 25 µl |
| Sample type: |
serum, plasma (EDTA, Heparin, Citrate) and cell cultures (epithelial cell |
| Sample preparation: |
Store samples at 2 – 8 °C up to 4 hours. For longer |
| Reference values: |
Cut-off < 200 U/L - 200 normal subjects, 95th percentile 251 U/L |
| Species: |
Human, Primates |
| Tests: | 96 |
| Method: | ELISA |