$100.00
Collagen resorption. C-Terminus of 3/4 peptide, generated through cleavage of types I and II collagens by collagenases
| Brand |
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| Intended use: |
C1,2C as a biomarker is used in the investigation of the progression of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, reflecting cartilage, ligament, skin, synovium/capsule, lung and bone damage or inflammation or repair, in human as well as some animal models. Increased serum C1,2C concentrations give an indication of a rapid progressive joint damage in RA. |
| Range: | 0.03 - 10 µg/ml |
| Incubation time: | 2.5 hours |
| Sample volume: | 25 μl (dilute serum 1:2) |
| Sample type: |
Serum (also used for plasma, urine, cell culture, tissue, synovial fluid, cartilage extracts, bronchoalveolar lavage) |
| Sample preparation: |
Serum samples should be aliquoted, rapidly frozen and stored at -70 °C. Avoid repeated freezing/thawing of samples. |
| Species: |
Human (also used for dog, bovine, horse, mouse, rhesus macaque, rat, guinea pig, sheep). The use of rabbit samples may lead to high background interference. |
| Cross reaction: |
Negligible cross-reaction with uncleaved triple-helical and heat-denatured human collagen types I and II and intact or cleaved alpha-chains of collagen type-II. |
| Tests: | 96 Tests |
| Method: | ELISA |