Adiponectin high sensitive ELISA (TECO®)

$379.00

Total Human Adiponectin

Brand

SKU: TE1013 Category:

Description

Intended use:

Adiponectin is a 30kDa protein and its percentage in serum proteins is 0.01%. In vivo, it appears with different oligomers and it is mainly synthesized by adipocytes. Until now, IGF-1 is the only known natural inductor of synthesis.
Low Adiponectin levels are closely associated with insulin resistance and metabolic syndrome as well as an increased risk of type 2 diabetes mellitus and cardiovascular disease.
Today, Adiponectin is thought to act as an endogenic insulin sensitizer by decreasing excessive glucose levels without increasing insulin concentrations and by stimulating the burning of adipose tissue in muscle and liver.
Adiponectin is associated with glucose and lipid metabolism and is assumed to have direct antiatherogenic characteristics. Furthermore, it is involved in inflammatory processes.

Clinical significance:
• Obesity
• Atherosclerosis
• Energy metabolism
• Coronary artery disease
• Metabolic syndrome
• Polycystic ovary syndrome (PCOS)

Specifications

Range: 1 – 100 ng/ml native Adiponectin
Sensitivity: < 0.6 ng/ml
Incubation time: 2 hours
Sample volume: 5 µl (dilute >1:300 serum and plasma). For other biological fluids see protocol.
Sample type:

Serum, heparin plasma, breast milk, urine, saliva, CSF, cell culture

Sample preparation:

Blood collection - fasting is recommended.
Samples are stable for maximum 2 days at room temperature. Long-term storage stable for maximum 2 years at -20 °C.
Max. 5 freeze and thaw cycles.

Reference values:
mg/l
Men Adult 8-10
Female Adult 10-12
cut-off 10

Comprehensive clinical reference data related to age and gender are available for this test.

Species:

Human

Tests: 96
Method: ELISA
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